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Mario Ammirati, MD, MBA
11199 Sorrento Valley Road, Suite 203, San Diego, CA 92121

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Practice Info

Practice Description

Neurological Surgeon


Neurosurgery of benign brain tumors, malignant brain tumors, brain metastases, minimally invasive spine surgery, skull base surgery.

Open Hours

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Dr. Mario Ammirati is a Board Certified Neurosurgeon who brings more than 25 years of experience in performing thousands of neurosurgical procedures. He trained in neurosurgery at Northwestern University Medical School. Afterwards, he completed a 2-year fellowship with Professor Samii, the leading world expert in skull base neurosurgery. He contributed to writing the guidelines for the treatment of brain metastases and brain tumors on behalf of American Neurosurgical/Cancer Associations. Dr. Ammirati was one of the first neurosurgeons in the USA to use computers and intraoperative Computerized Tomography (CT) to place instrumentations (screws) in the spine, thereby decreasing the number of badly-positioned screws and hence the need for reoperation while optimizing patient outcomes. Since the beginning of his career in 1989, Dr. Ammirati has personally trained more than 120 neurosurgery residents and fellows from all over the world in the delicate art of neurosurgery/skull base surgery and spine surgery. These surgeons have used the techniques that they learned from Dr. Ammirati at prestigious neurosurgical institutions such as, amongst others, Harvard and Cleveland Clinic. He is also one of the world’s foremost leaders in diagnosing, removing and treating benign brain tumors with care and precision, while prioritizing his patients’ quality of life and physical functions. He prides himself in being the most considerate doctor to his patients, who meet him at the most vulnerable time in their lives. Dr. Ammirati’s treatment philosophy is based on adherence to the most up to date reliable scientific evidence that is tailored to the need of each individual/unique patient. Indeed, no guideline completely fits each unique patient. Dr. Ammirati has contributed chapters on Skull Base Surgery in the last 3 editions of the #1 neurosurgery textbook in the world (Youman’s Neurological Surgery), and his contributions to the advances of medicine in general include authoring 13+ textbooks on skull base tumors and meningiomas, speaking at hundreds of conferences over 40 years, and publishing more than 165 peer-reviewed research papers that uncover and perpetually evolve techniques to improve outcomes and lives through neurosurgery.

Medical Organizations & Memberships

American Academy of Neurology

Medical School

Medical School, University of Naples, Italy

Medical School


Year of Graduation



November 1977 – October 1981 Resident, Neurological Surgery, magna cum laude Medical School, University of Naples, Italy
October 1980 - June 1983 Resident, Neurological Surgery Northwestern University Medical School, Chicago, Illinois
July 1983 - June 1984 Resident, Surgery Memorial Sloan-Kettering Cancer Center, New York, NY

Advanced Training

July 1984 - June 1987 Resident, Neurological Surgery Northwestern University Medical School, Chicago
July 1987 - July 1989 Alexander von Humboldt Fellow, Skull Base Neurosurgery
May 2003 - July 2005 Temple Executive M.B.A. Program


2015 "Top Cancer Doctor" by Newsweek Magazine
2007-2016 "Best Doctors in America" peer-reviewed award

Languages Spoken


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